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PRENATAL DNA TEST

DNA Paternity TestFor people who want to know the paternity of their unborn child, similar to the standard paternity test, the prenatal test compares the baby's DNA profile with that of the alleged father. Because the baby's DNA is set at conception, the prenatal test gives the same conclusive results as the standard paternity test. The paternity of an unborn child can be determined utilizing the same laboratory methods used in conventional paternity testing. Prenatal DNA from an unborn child is collected and compared to DNA from the mother and the alleged father, whose DNA is collected using conventional buccal swab techniques.

 

DNA Paternity Test

 

 

NEW: Non-Invasive Prenatal Paternity Test - 1-888-312-4362 The most accurate non-invasive way to establish paternity before the baby is born. The process is state-of-the-art, combining the latest in DNA SNP microarray technology and proprietary methods of preserving and analyzing the baby's DNA found naturally in the mother's bloodstream.

  • Accurate results in just 5 business days
  • Requires only a simple blood draw from the mother and alleged father (a fetus' DNA is found naturally in mother's blood)
  • May be performed any time starting in the 9th week of pregnancy
  • Conveniently located blood collection locations

Is this test more accurate than the Amnio or CVS Prenatal tests?
Amnio / CVS prenatal test is equally as accurate.

What is the difference between this test and an the Amnio or CVS Prenatal tests?
Drawing blood is a non-invasive procedure, this alone makes it a safer, convenient, procedure.

May this test be performed for Twins or Multiple Fetuses?
No, this test is validated for single fetuses.

May results of this test be used for legal purposes?
Yes, because a strict chain of custody is maintained and documented during the specimen collection process, each person collected is positively identified.

How accurate is this test?
It is the most accurate non-invasive prenatal test available. Testing is >99.9% accurate in determining whether the tested alleged father is indeed the biological father. The test utilizes the latest state-of-the art technology to look at the baby's DNA in the mother's blood.

How is the test performed?
Participants' DNA specimens are analyzed using a dense microarray technology to examine 317,000 genetic markers (a/k/a single nucleotide polymorphisms (SNPs). Utilizing free floating fetal DNA (cfDNA) isolated from plasma of the Mother's blood, along with DNA profiles from mother and an alleged father. An informatics algorithm (Parental SupportT) is used to compute the similarity

What results may one expect?


  1. Paternity Inclusion: The alleged father is not excluded as the biological father of the fetus. The probability of 99.9% that the tested alleged father contributed his genetic markers required of the biological father is 99.9% when compared with random individuals.

  2. Paternity Exclusion: The alleged father is excluded as the biological father of the fetus. The alleged father lacks the genetic markers that must be contributed to the fetus by the biological father.

  3. Insufficient fetal DNA for conclusive analysis: An insufficient amount of fetal DNA was present in the mother's blood; therefore determining the paternity of the fetus is inconclusive. Because the amount of fetal DNA in maternal blood varies greatly during pregnancy and increases with advancing gestational age; a recollection of the mother's blood only is required for the testing to be repeated.

  4. Indeterminate paternity results: No conclusion regarding paternity can be determined from the genetic testing performed. The statistical value obtained for the tested alleged father is inconclusive and, thus, he can neither be included nor excluded as the biological father of the fetus. This may occur for various reasons including, but not limited to, close genetic similarity between an alleged father and the true biological father. Because of genetic similarities among relatives, DNA specimen collection (blood draw) from all possible alleged father's is recommended if they are related.


DNA Paternity Test

 

 

Pre-Natal Collection


The prenatal DNA can be collected by a physician utilizing one of two techniques: amniocentesis or chorionic villus sampling (CVS).  The type of sample collected will depend on the stage of pregnancy.  CVS is typically performed between the 10th and 12th weeks of pregnancy, while amniotic samples are collected between 12 and 21 weeks.

DNA Paternity Test
Amniocentesis is an invasive procedure that involves inserting a needle into the mother’s abdomen to withdraw a small amount of amniotic fluid from the amniotic sac which surrounds the developing fetus.  This procedure can lead to damage or loss of the baby in up to 1% of cases.  As a result, it is recommended that patients wait until the baby is born, unless they are already undergoing this procedure for medical reasons.

In general, a 10 ml sample of amniotic fluid is requested.  Samples can be collected in sterile non-preserved vials.  Samples collected prior to 18 weeks gestation may contain insufficient fetal DNA for analysis.

Chorionic villus sampling involves inserting a catheter through the cervix and removing portions of the chorionic villi. Chorionic villi are microscopic finger-like projections that emerge from the chorionic membrane and eventually form the placenta. The cells in the chorionic villi are of fetal origin, and thus have the same genetic composition as the baby. This procedure can lead to damage or loss of the baby. As a result, it is recommended that patients wait until the baby is born, unless they are already undergoing this procedure for medical reasons. Samples should be shipped frozen on dry ice to the laboratory via overnight courier.


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